There are basically two differences between S/S and non-S/S OEM fitments; the EFB S/S battery can be safely charged at a higher rate, and is capable of a greater number of charge/discharge cycles before failure. All else being equal, the EFB battery will be longer lasting, irrespective of whether S/S is fitted or used.
Both are flooded cell 12V lead-acid batteries, and when first installed, both should give the same performance. However, if you fit a non-S/S battery and don't disable S/S in the menu, it likely won't last anything like as long. Bear in mind also that the S/S 500 has a higher output alternator, and a non-S/S battery, if significantly discharged, might be compromised by the increased charge rate.
Figures I've seen suggest an EFB battery is good for about 70,000 starts, as opposed to 30,000 for a standard one.
Another thing to bear in mind is that fitting a non-S/S battery to a S/S equipped car will likely invalidate the battery warranty, irrespective of whether you actually use S/S or not.