On the seicento there was very little to take off to get to the valves and I think the panda will be similar (not looked under the bonnet of a petrol one though) and then the practical side of it still applies.
The rule of nine still applies as these basically still the same as any engine built in the 60s. Bar the cambelt and the alloy head.
If you do a search you will find the clearances on the forum somewhere, might take some finding but they are there. Otherwise someone with a Haynes manual will be able to find them straight off.
The biggest problem is when the valves actually need adjusting, it is nowhere near as simple as the old A-series Mini I have at home which is a 7/16" spanner and flat screwdriver. For the Fiat you need to measure the cam clearance and if incorrect then remove the cam follower and check the shim underneath. There will be a measurement on the shim and you can then go and get a new part from Fiat with the correct amount added or subtracted. I have heard of some Volvo ones that fit and also people go to the local machine shop to get some made of the correct dimensions. Getting the proper ones helps you out for the next time or the next person who needs to do it. The only problem being if it is your only transport you will have to reassemble it to go and get the parts.
The shims can be removed without removing the cam, I used two flat screwdrivers as levers to wriggle the parts out, one to push the cup that the follower sits in down and the other to flick the follower out. Beneath this you will find the shim.
There is a reasonable tolerance on the measurements too so they dont have to be precise, it is sometimes best to leave it and check at the next interval. The theory behind this is the valve wears into the head at the same speed the cam/follower wear. In the UK with good fuel, reasonable temperatures and quality oil (even the cheap stuff) there should be minimal wear.
In the bikes vs cars comment I would do the panda valves anytime over the ones in my Suzuki SV1000 which are coming up in a few thousand miles. The rear head is under the seat/tank support, has a load of emissions related pipe work in the way and the main bike wiring. The front isnt much better and really needs the radiator removing to do a proper job.