Hmmm, maybe.
What also happens is that when you lock the door either with the key or by shoving the door pin down inside, you force the door lock motor past it's 'seated' position.
The seated position is where the central locking motor sits at rest, in a groove so to speak. If you have remote central locking, it gets an electrical signal and tells the doors to lock. The motors drive the locks closed, relying on them not slipping from their seated position. They close an electrical contact, telling the central locking system that it has closed properly and life is good.
If they don't stay in their 'groove', the door will remain unlocked - the lock pin won't be pulled down or pushed up as requested and the required circuit won't be made. The central locking system will say 'hey up, the boots locked, one door's locked but the other's not playing ball for some reason. Nuts to this, I'm gonna open it all again"
When you use the key or door pin to unlock or lock, what happens is you force whichever lock motor out of it's 'groove', lock that door and make the circuit. Central locking system wakes up and says "oi oi, lock (or unlock) time" and puts the other motors into the same position as what you've just done with key or pin. Motor you have just forced then sits back in it's 'groove'. If any one of them doesn't make the circuit, it'll go back - i.e. do the opposite of what you've just tried with key / pinky.
So, using the key or door pins, you force the motor out of it's groove. This will in time cause wear, which can mean that when it's asked to lock or unlock by electrical means that it slips. Slip can be caused by old age and stiff mechanisms too.
I'd recommend you clean and lubricate the lock mechanisms inside the doors, and check to see if one of the motors is slipping by using the other side door key / pin. If you force the 'bad' one, the system should work fine.
Enormous fun can be had in the ice with this. You unlock the door with the key or remote locking, but one mechanism is frozen. Theoretical machine based communiccation goes a bit like:
(key) Open sesame.
(locking ecu) Bugger off, I'm locking it again.
(key) open again please
(locking ecu) Oi, I told you, bugger off. <locks doors>
(key) Let's not be silly, It's cold and I need to go home. <opens locks>
(locking ecu) You ain't coming in here, one of my motors says No. One out, all out squire. <locks gates again>
(key) Right, you electronic things always think you know best. Bugger you. <opens lock and person opens car door at same time>
(locking ecu) Eeeeek - I've got one open, one locked and I'm al confused. I'll unlock and lock all the doors repeatedly until something happy goes on.
(key) haha, I'm in.
(locking ecu) Right, I've locked them and they're staying locked. I'm happy.
End of story - driver is in car, driving home. Central locking is locked, but he don't care for now. It'll probably be defrosted by the time he gets home anyway.
The freezing scenario can be reproduced by a sticky motor if you follow it through.
On balance though, reading this - I think I need to up my doseage. Nurse!