It would seem you have a similar fault to a van I'm having a look at. No feed to the EGR which was traced to the ECU. upon moving the fuse box I have now developed 2 lives missing at the ECU which were traced back to the main relay T09. It would appear that this is basically an earth problem which is controlled by the ECU. Add to that I now have the Key lock light on and NO engine light on. All of which stemmed from moving the wires around the fusebox and ECU.
Ive not had chance to look further due to prior commitments and poor weather but will keep an eye on this thread
Anyway to answer your question with the x250 book you have obviously downloaded you will find the ECU pin out numbers and the wiring diagram, in fact all the needed info is in the download.
looking at your diagram (found on pg 84ish), M010 is your ECU and the plugs on the ECU have letters relating to the connection block (pg59ish for ECU pin out numbers the fuse box is also in the book) and the orange/white wire goes from pin 10 on the fusebox C block to pin G1 on B connection to ECU. So with the wiring scematic you can trace the wires from and too their relevant connections.
on mine I found that the main relay (T09) powers fuses 11, 17, and 22 which are 2 lives to the ECU and the glow plug relay
F11 pin out No7 conn C of fuse box goes to pin 6 of glow plug relay
F17 pin out No31 conn C of fuse box goes to pin H2 on plug C at ECU
F22 pin out No18 conn C of fuse box goes to pin H1 on plug A at ECU
pin 85 of the main relay(T09) is basically an earth which goes from pin 10 connection C of the fuse box to pin G1, plug B at ECU so it is controlled by the ECU which is the orange/white wire you mention.
be warned that where lines cross they are only connected if there is a black dot which is more noticable in the fusebox (B001) or a diamond shape if out of the fusebox.
hope this explains it better for you,
Work through the diagram slowly and make yourself familiar with it. It took me 3/4 times to fully understand it so good luck keep the thread udated as will I as it is very similar fault