You can build a fairly big sealed door pod to replace the whole door pocket (a la Paul)
But even I'm thinking of destroying the door and venting, not sure yet.
For tweets, I have mine where the factory speakers sit. Not 100% sure about this, the imaging isn't great and they sometimes sound quite harsh. This could be down to the tweeter though. I am now in the position to run a rully active setup, so I'm going to try the old blue tack trick at some point to see if I can improve things.
I've heard some amazing setups with tweets in the kicks.
Mids (well, in this instance midbass / midrange - playing from say 70hz to 4000hz) is a difficult one in a 'Cento as Dai says. From what I can gather, mounting them high up is a bit of a no-no. Problem with the cento is there's so little room, mine are mounted flat against the door build, imaging wise I not sure if that's a bad thing or not. You're closer to one, but more direct to the other. Having them "facing you" would mean they would have to stick out a huge amount, especially if you're using a 6.5" driver.
Again, I've heard stunning front ends with the driver in factory location (ie, door, flat) so perhaps it doesn't effect things too much????
I'm hoping to get all the equipment (crossover, EQ's, mad PG remote turn on thing) in my car over the next few weeks and then take it to my brothers mate to see what improvements can be made. I could spend days farting about when someone with a clue what they're doing would sort it in a few hours.
Then there's the big TalkAudio event but it's frickin miles away so not sure if I'll be attending that one.