Hi. I have a Ulysse mark 1, 2003. Replacinng timing belt. Have found slot on fly wheel, where are the marks on the pulley I can find no hole to insert timing locking tool on timing pulley which looks nothing like that in the works manual

Are you sure it is a mk1? 2002 is the year that the Ulysse mk2 came out.

If so it is a different engine 16 valve as opposed to 8 valve

The OP doesn't state the engine type fitted to his car. For the 16V 2.0 JTD (diesel) there is a cut-out slot on the boss of the camshaft to which the camshaft toothed pulley is bolted. The timing tool (or suitable diameter drill) goes through this slot into a timing hole in the cylinder head when the crankshaft is at the correct timing position.