item 11 on right hand side is thermostat. 10 is the seal. Not sure what 12 screw and washer assay.
Looks like a pretty straight forward item.
Ideally you want to look for the lowest point in the system, like bottom radiator hose and pull that first to drain the system. Otherwise you risk soaking everything in coolant as you remove the stat.
So drain system first. Coolant is highly toxic and poisonous to animals so you can't just tip it down the drain. If you do spill any onto your drive / garage, road, be sure to clean and rinse thoroughly so you don't harm anyone / anything.
The new stat should come with a new seal. Check the job out before hand to make sure that where they've used silly fiat clips that you've got the correct size jubilee clips to replace them with. You can re-use the old ones but for the cost they're so much easier to replace.
Before you remove the stat itself place an old towel or something underneath it to catch anything that spills out - as some will. You want to avoid any falling into the bell housing if they have inspection holes or anything like that.
Once removed you'll no doubt have some crustiness around the mounting surface, give that a rub down for a nice clean seal and re-fit.
Top up with new and correct type coolant (Halfords have a guide book on the shelf to advise which type you need) and run the car up to temperature. As the stat opens for the first time you'll no doubt find that the coolant level drops right down so you'll need to top it up some more until you get the air out the system. You might need to squeeze / pump on the top hose a bit too just to get things moving and tease the air out.
Have fun.